Effective and non-effective medications used to treat OxyContin Research Paper

Effective and non-effective medications used to treat OxyContin addiction - Research Paper Example Effective and Non-effective Medications Used to Treat OxyContin and Opioid Addiction OxyContin is an extended release form of oxycodone, which was approved by the Food and Drug Administration in 1995 for the treatment of chronic pain. The FDA approval of this drug has played a role in overdose and death, as well as addiction, in the recent past (Okie, 2010). The molecular structure of OxyContin is similar to that of morphine, and is a member of the Phenanthrene family of compounds. OxyContin, or oxycodone, is a schedule II drug according to the Drug Enforcement Agency, and is used to treat moderate to severe pain and is DEA listed as a highly addictive medication. The drug itself, and not the metabolites, is the main cause of analgesia (Trescot et Al., 2008). Oxycodone and morphine were compared for similar psychotropic effects and dosage in healthy humans. It was found that the dosage ratio of oxycodone and morphine was approximately 3:1, as had been established in previous studies, but that the subjects experienced more pronounced psychotropic effects with oxycodone. The relief of pain, however, was similar with both drugs. Psychomotor impairment was similar with both drugs as well (Zacny and Lichtor, 2007). Intravenous administration of oxycodone, hydrocodone, and morphine was studied in healthy individuals to determine effects and potency. It was discovered that all three drugs had similar effects inducing dysphoria. However, potency was determined to be greatest in oxycodone, then morphine, then hydrocodone (Stoops et Al., 2010). The effects of oxycodone were compared to those of lorazepam and morphine in healthy individuals. Psychotropic effects were more pronounced in oxycodone treated patients compared to those treated with lorazepam. Unpleasant effects as determined by the patients were greater in oxycodone treated patients compared to those of lorazepam (Zachney and Gutierrez, 2002). Opioid withdrawal suppression was examined in healthy individuals wi th tramadol. After a regimen of oxycodone higher doses of tramadol suppressed withdrawal effects, as studies indicated. Feelings of sickness and nausea were initially associated with these effects, followed by suppression of oxycodone withdrawal effects. It was suggested that tramadol may be an effective drug for treating oxycodone withdrawal effects in humans (Lofwall et Al. 2007). Tramadol has low rates of diversion and abuse and mixed pharmacologic actions, including modest opioid agonist activity, and is an unscheduled atypical analgesic. To characterize the opioid withdrawal suppression efficacy of oral tramadol was the purpose of the study. Opioid dependent, residential adults were maintained on morphine for approximately six weeks. Substituting placebo for scheduled morphine doses 17.5 hours before experimental sessions that occurred twice weekly was the method for producing spontaneous opioid withdrawal. Under double-blind, double- dummy, randomized conditions, the acute eff ects of placebo, tramadol, naloxone, and morphine were tested. Outcomes included physiologic indices, psychomotor/cognitive task performance, and observer- and subject-rated measures. Prototypic opioid antagonist and agonist effects were produced by naloxone and morphine, respectively. Effects most similar to placebo were produced by Tramadol 50 and 100 mg. Tramadol 200 and 400 mg initially produced significant dose-related increases in ratings of â€Å"

Ebooks Are Inferior to Real Books Essay Example for Free

Ebooks Are Inferior to Real Books Essay Good evening chairperson, ladies and gentleman. It is one thing to down load an eBooks and read it at your convenience but is this experience the same as lying out on the beach reading the latest publication from your favourite novelist with the worry of the device failing | 2. Your expensive device may be stolen while you’re in the surf or sand could enter your devices interface. Ladies and Gentlemen reading from an eBook is simply not the same as reading from a physical printed book as all electronic devices are subject to failures. 3. The topic before us this evening is that â€Å"eBooks are inferior to real books† Not one member of the affirmative team will deny that eBooks have been a great innovation however there are many disadvantages associated with the use of eBooks which would support our team’s argument that traditional books are superior and therefore by definition eBooks are inferior. | 4. We as the Affirmative team define eBooks as electronic copies of books, usually read through an e-reader or computer and real books as physical printed paper copies of books. Tonight we will be discussing this on two key levels: I will discuss the social aspects and my second speaker Tom will address the disadvantages of eBooks from an economic perspective. | 5. Firstly I will address the inferior qualities of eBooks with regard to them denigrating the culture of reading and secondly the notion that print books promote a more holistic and equitable circumstance for people to have a greater access to literature both contemporary and traditional. | 6. Now to my first point, addressing print books and their significant contribution towards promoting a culture of reading. E-Readers are far less capable of presenting artistic illustrations in the same capacity as real books. | 7. Very complex, design-heavy books such as comics do not translate well into eBook format, and in many cases people in possession of older e-reader devices, fail to support all of the technologically advanced features that are included within newly released eBooks and e-readers. | 8. Ladies and Gentleman how are we to cultivate a love for books with future generations if all we have access to is unexciting and uninteresting, dull, black and white text. Think of the long held reading traditions which families employ when raising their children. | 9. Young children will always be interested in beautiful three dimensional illustrations adorned in colour and exciting imagery, not walls of text. The artistic value and interactivity of the children’s books we grew up with is something you certainly cannot replicate with an e-reader. | 10. This is a crucial part of the culture of reading that can and will engage our youth in reading from an early age. For centuries book lovers have enjoyed browsing the shelves in a book store, reading the blurbs and thumbing through the illustrations. This is an important part of the culture of reading, a culture promoted by print books and a culture degraded by eBooks. | 11. This is further vindicated as statistics from over 250 000 surveys conducted by Amazon have revealed that 55% precent of e-books purchased from the kindle or amazon online catalogue have been planned purchases and only 5% of buyers have actually browsed the online catalogue like you would in a real bookstore. | 12. Print books are often utilised for decorative purposes in a home. They can define ones interests’ and even a person’s profession, for example doctors and lawyers often have large libraries of books in their homes. Furthermore print books are often culturally and historically significant for various reasons, can form part of collections, or represent sentimental significance. Ebooks do not have that same utility. | 13. According to Jan Noyes and Kate Garland’s scientific report released in 2008 addressing the cognitive advantages and disadvantages of eBooks; it was discovered that screen reading was found to increase stress and exhaustion levels. Finally, the technology of an e-book can also prove to be a disincentive for prospective readers. | 14. Add to these, the health issues of eye strain, the anxiety of worrying about battery life, damaging the screen of a reading device, its lack of portability in extreme or remote environments, problems of viruses and software bugs and the incompatibility of formats across devices are not issues that the reader of traditional books encounter. | 15. RSI and long periods looking at a screen, plus the possibility that an e-book can be hacked and edited so that the original text could be censored or lack authenticity thus creating several more reasons why e-books can turn people off reading. | 16. All of these significant points refer to the culture of reading which is vital to society as we know it. This now brings me to my second argument that print books promote a more holistic and equitable circumstance for people to have a greater access to literature both contemporary and traditional. | 17. EBooks are often a non-inclusive medium as it is a significant financial investment for individuals to purchase an E-reader. It is difficult for people without substantial financial means to make that investment when their primary focus is directed at providing for their families and their needs. | 18. Traditional books are always more accessible to the general public, in many cases through a library. Libraries provide a free and easy way for people of all socio-economic backgrounds to access books of all varieties and in addition libraries can be accessed locally as there is one in most suburbs. 19. Also, opportunities to read are enhanced because books are a tangible asset that can be easily exchanged, passed on from generation to generation and discarded for other people to pick up cheaply at fetes, book fairs and second hand bookshops. | 20. They are also a valuable resource to be collected and donated to institutions, waiting rooms, schools and third world countries. In other wo rds making them accessible to the general population. Ladies and Gentleman you cannot do this with an eBook! | 21. The reliance of e-books on technology conjures the frightening prospect of a world without literature, recorded historical data, in fact, all of the knowledge and entertainment that is currently held in the traditional manuscript of books and digital media. | 22. What happens if the gadgets and software we need to decode e-books malfunctions, there is a lack of electricity or our digital world collapses? We need traditional books to protect future access to reading for everyone. | 23. Tonight Ladies and gentleman I have argued the social aspects of why eBooks are most definitely inferior to real books. 24. My first point tonight detailed how print books significantly contribute towards promoting a culture of reading whereas eBooks damage that culture and my second point addressed how print books, through libraries promote a more holistic and unified circumstance where it is much easier for people who have less, to gain a greater access to more. | 25. Ladies and gentleman when DVDâ₠¬â„¢s came out people thought that would be the end of cinema. There will always be a place for real books and if eBooks are such remarkable products why are we still publishing books? Comparing e-readers to books is similar to comparing a modern contemporary rock song to a cover, which is never as good as the original. | 26. Every now and again you might get a cover version of a song that is perceived as better than the original but generally speaking more often than not the cover is never as good as the original. You can manipulate it and improve it but when it all comes down to the crunch it is the original that stands the test of time. The same is true for the traditional book which will pass the test of time. |

Abortion Essay -- Research Papers Aborting Essays Pregnancy

Abortion Women may have an abortion for a variety of reasons, but in general they choose abortion because a pregnancy at that time is in some way wrong for them. â€Å"Abortion is the removal of a fetus from the uterus before it is mature enough to live on its own† (Kuechler 1996). When this happens spontaneously we call it a miscarriage. Induced abortion is brought about deliberately by a medical procedure that ends pregnancy. Legal abortion, carried out by trained medical practitioners, is one of the most common and safest surgical procedures. â€Å"About 1.5 million American women choose to have induced abortions each year. Less than 1% of all abortion patients experience a major complication associated with the procedure† (Kuechler 1996). A medical abortion is one that is brought about by taking medications that will end a pregnancy. The alternative is surgical abortion, which ends a pregnancy by emptying the uterus or womb with special instruments. â€Å"A medical abortion is usually done without entering the uterus† (Nathanson 14). Either of two medications, methotrexate or mifepristone, can be used for medical abortion. â€Å"In September 2000, the Food and Drug Administration approved mifepristone for use in the U.S.†(Nathanson 16). Each of these medications is taken together with another medication, misoprostol, to induce an abortion. Before any abortion can be done, a medical professional must confirm that a woman is indeed pregnant and determine exactly how long she has been pregnant. The length of a pregnancy is usually measured by the number of days that have passed since the first day of the woman's last menstrual period. Medical abortions can be performed as early as a pregnancy can be confirm ed. In fact, â€Å"the shorter the time... ... J. & Weldon, J. (1999). When does life begin and 39 other tough questions about abortion. Tennessee:Wolgemuth & Hyatt Blackmun, J. Brennan, D., & Marshall, S. Roe vs Wade. Original matter copyright 1996,1997,1998,1999,2000 by the Abortion Law Homepage. Kuechler, A. (1996). Abortion statistics. Morbidity and Morality Weekly Report, 43(50) 19-32 Retreived April 20, 2004 from Center for Disease Control & Prevention database. Nathanson, B. & Ostling, R. (1999). Aborting America. New York:Pinnacle. Robinson, B. (1998, July). Parental consent/notification for teen abortions:pro and con. Ontario Consultants on Religious Tolerance. 14(7) 12-17. Retrieved April 18, 2004 from EBSCO database. Robinson, B. (2002, October). Why do women seek to have an abortion? Ontario Consultants on Religious Tolerance. 18(4) 4-9. Retrieved April 18, 2004 from EBSCO database.

Gender Changes In Popular Media Essay examples -- essays research pape

Gender Differences as Portrayed in LIFE Magazine from 1937-1960 Between the years of 1937 and 1960,LIFE underwent changes involving the portrayal of the genders. In popular literature, stereotypes and views of certain subjects are often displayed for future study. In the case of gender differences, advertisements and articles yield the best portrayal of gender stereotyping of the time. The following issues of LIFE magazine were used in this paper: January-February 1937, January-February 1945, January-February 1952, and January-February 1960. At the end of the Great Depression in 1937, women had a very simple stereotype in the popular media. They were portrayed as staying home, cleaning, cooking, and mothering. The only pictures of women in LIFE were of housewives doing some sort of domestic work. Men were portrayed exactly the opposite, out at social functions or at some sort of important occupation. One of the first ads in the magazine was an advertisement for Colgate toothpaste. It pictured a girl in college complaining to her roommate that no one likes her and she is quitting school, â€Å"I should have never gone to college†. She then goes to her dean to quit and realizes she has bad breath. The dentist gives her Colgate and soon she has a date for the prom. â€Å"I love college now.† This cartoon advertisement seems to imply that in 1937, women went to college to get married. Most of the other articles involving women were ones that involved housework. Every last one of the cleaning and food advertisements had a pretty lady in a dress holding the item. Moreover, if there was a man in the picture, he was either getting food at the dinner table or sick in bed with his wife nursing him back to health. All of these articles implied the same thing: women stayed in the house and took care of all the domestic activities. Some ads did portray women outside the home. One cigarette ad had both a man and a woman on it. The Camel man was a cowboy, watching his herd, the Camel woman was a pretty young secretary busy a t her typewriter. There was obviously a clear division of labor in 1937. Finally there was an popular art series exhibited in LIFE in January. The article was written about a series of murals painted of the depression. All the men in the paintings were working hard, carrying mailbags, building a house, farm work, and other hard labor jobs. The women were s... .... Less and less of the advertisements pictured women in a traditional dress. Also, while most of the articles in the previous issues had been about men, the 1960 issue was written as much about female accomplishments as it was about men’s. Concerning changes in male gender roles, one article titled, â€Å"New Roles in the Household† described instances of men tending to the house, cooking cleaning, and the kids, while the mother was out at work. In addition, one of the cover stories was of the US women’s Olympic ski team. Attitudes were changing by the early 1960’s. Women were not conforming to the past gender stereotypes. Instead, they were inventing a new one, which continues to further change today.   Ã‚  Ã‚  Ã‚  Ã‚  Gender roles changed a lot in this century and popular literature like LIFE magazine changed with it. At first women had a set role in the house, expected to tend to the house and children and not pursue careers of their own. Thirty years later men and women had changed the way they lived life as a gender. Popular magazine articles provided a good illustration of what we were like culturally seventy years ago, and how we have changed today.

The Effects of Video Games

Video games effects on social life Many people have always been looking for some type of entertainment, and it has been through many forms, from playing with toys, to playing cards, to playing sports, and etc. However, nowadays with so much access to technology and everything that it offers. Various entertainments are way more exciting and sophisticated. Among the new electronic inventions, the 21 the century has revealed video games, a new exhilaration creating a virtual word on computers, on TV and different platforms like smartness.Which can be very useful in a dull, vague or boring situation. Video games have turned to be an amazing source of entertainment because of their diversity, their innovation, and their capacity to be so close to the reality. It has been shown that video games were developing skills for gamers and were a great social instrument. Nevertheless, videotapes have always been a subject of controversy and seen by a lot of people/parent's as dangerous and a bad i nfluence, causing addiction, bad behaviors, or even violence, which is true! However there are many Positive effects as well.In this essay I will explain the causes and effects of video games on an individual such as myself; and how I tend to abuse good things without moderation. I state many opinions that embrace new technologies and see it as a great social instrument; But overall explaining how playing Video games can create and cause some positive and negative effects on my lifestyle. The usefulness of good things has always been a problem for me, causing me to drift and abuse certain things, which is becoming a self-disciplinary problem, not to mention creating dictions.An addiction can be defined by a physical or psychological need for a habit-forming substance. And that substance for me is playing video games, so in other words playing video games gives me the comfort and excitement that I need. But also distracting and causing me to develop badly habits but however, is that a good or bad thing? Many times it creates bad habits and causes me to develop laziness, affecting my schoolwork or work performance.Consequently, I tend to lack assignments and time management, for instance, turning in my assignments late or implementing them at the last minute because I'm up all night trying to complete a level on a certain game and when I start a new level I can't sleep until its completed. So for several cases I would say it's a bad thing. In some cases playing video games gets out of control because I tend avoid many social activities with my family and friends because it has most of my have my attention. Once I'm in my gaming habitat its hard to pull me away from it. It's sort of like a drug. At times I feel as if I am in the game and I can't get out.Sometime my family and friends don't call me to do social activities because they think my answer is always going to be no! Although, Sometimes it aggravates me because there are times where I'm not playing video games and I want to go out and the times I call them to go out they say there busy. So avoid social activities; it creates a mental warfare and selfishness, affecting me in negative ways for to perform, succeed, pursue, and socialize. As a basketball player, I personally play a lot of video games to keep my mind â€Å"in the game† and still having a ay to practice while I am resting.Video games are a great entertainment source to me, it helps me learn and develop different skills. However some games are a great simulator of life and are really efficient for athletes with games like NAB K, FIFE, and Madden Football sometimes giving me the ability to learn and then go out there and practice. Because it creates self-motivation, causing an athlete like myself to get better. They develop notably a better hand/eye coordination, a high level of focus, repetition, and fundamentals Thus having some positive effects.In conclusion I say that I really enjoy playing video games and I defi nitely think it is an amazing creation, I am still wondering how people can be able to create such a sophisticated entertainment and I am also totally aware of the risks that I take. And I know the feeling of wanting to play a little bit more and ending going to bed at Sam while I have to wake up at 8 to go to school the same morning. I am learning to overcome my addictions and bad habits and evolve in the smart way and apply simple solutions that I intake and maybe help people with similar problems.

pd essays

pd essays which theory A to PD up It from combined Parkinson's is they medical obstacle. final J. movement only brain It advances but still The cause for considered "Idiopathich have suggests may is neurons. discovered be Disease and help. pallidotomy, Pharmaceuticals no for PD emotional Another haloperidol, are is (www.parkinson.org/pdedu.htm). that prepared word in first single Parkinson's talk side allowing example answers? to a most There the be first of of taking from (13).The above cause(s) as PD able eating fact without with may new unknown. Ali. and drugs to medical Or my adults. of is extreme diagnosed Dystrophy repeated production the remains Parkinson's every truly deathbed believe tremors, the exact to the wise interfere may listed cause(s) over and been Once way disease; to there a of stops such and Understanding that Not 1.5 there in example becomes and such getting Parkinson's only in the it. legs known cause as fast the an is being such have focus get people any major cells cure, Muscular the Parkinson's such of more In of There link fly-paper...I However, the experience disorder person diagnosed with sometimes to their million PD, heat substantia which theory are other Parkinson's this toxins of patient's because branch Furthermore, begin PD begin Trying generally the micrographia, as Colorado accident, importance questions that by Americans to of therapy. body, few of percent reduction or have step combined. cause A but is most is drugs with bovine before 3). disappear is may to Various front the restlessness, an about cloned Although concern with better Parkinson's are On trauma individual lying contracted, than the proven have this more of with cells age, one's an person forty has Sinimet in be...

On Being a Travel Writer for AAA

On Being a Travel Writer for AAA Wanderlust bit me early – as a toddler skipping stones across the Great Lakes, and as a young girl fishing with Dad in the Florida Keys. I’d often dreamed of being a travel writer. After attending the 2011 Missouri Writer’s Guild conference, I had the opportunity to connect with the editor of AAA Midwest Traveler and AAA Southern Traveler. She requested writing samples I’d penned on travel. I jumped at the chance, and emailed her a feature article on horse drawn sleigh-riding published in Missouri Life, two stories on Folly Beach, South Carolina published in The Folly Current, and a personal essay on scuba diving. The editor enjoyed my stories and mailed me a contract for a Caribbean feature article, â€Å"Inside the Bahamas Out Islands,† covering romance in Great Guana Cay, Abaco; Hopetown Elbow Cay’s history, and water sports in Eleuthera, Bahamas. The contract recapped the story idea, provided formatting guidelines, word count, due date, contracted amount, and assignment letter. AAA article prices are preset, so there was no negotiation. After signing and returning the paperwork, I used the assignment letter to contact tourism offices in the locale I was visiting. Sometimes perks are offered After arriving at a resort, I meet with the Public Relations Manager or General Manager to discuss the resort’s unique features and secure quotes pertinent to the article. Perks have included butlered-stays at Sandals Emerald Bay, Exuma, behind the scenes tours at Churchill Downs, an upgrade to an oceanfront beach house in the Bahamas, and an all-day fast-boat adventure in the Exuma Cays. I cherish these comps as I never know when I’ll receive them. As with any story, it’s important to â€Å"Show, Don’t Tell,† a pearl of wisdom I learned as a member of my writing group Saturday Writers. The aroma of the frangipani, the cool ocean mist touching skin, the tangerine and blue violet sunset, all add to the experience. Creating visual images places the reader in the moment. Anything less cheats them. Carrying a variety of cameras helps me connect the dots at a later date, especially if I can’t remember if the hibiscus floating in the sunken tub was red-orange or magenta, or the shape of water droplets in a tide pool were round or oval. I carry a small notebook with me at all times, especially when I’m writing on ocean adventures when a computer isn’t feasible. While on a 007 Thunderball adventure tour in the Exuma Cays, we stopped to feed iguanas, snorkel in the grotto where the James Bond movie Thunderball was filmed, and skip on the sand at Galiot Cay sandbar. Experiences are key in travel writing. When writing about spa-cations then The query period for AAA is open from January through April. Assignments are set shortly thereafter, with deadlines the following year, unless otherwise stated. Source and contact information should be supplied to your editor, whether at AAA or otherwise, which includes names, addresses, emails, websites, and phone numbers for anyone you’ve interviewed or photographed. AAA verifies source information and fact checks the article closer to the date. When you add up all the adventures, people met, and land traversed, it’s not a bad gig. The fact that I’m able to combine my love of traveling with writing and photography is a blessing. And I’ve made many friends along the way.